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A data-driven breakdown of Vayne Mid for patch 16.17: the most-played and highest-win-rate builds and runes, the matchups that beat Vayne, synergy partners, and how Vayne closes games — all from ranked Emerald+ data.
Vayne is an AD carry in the mid, and on patch 16.17 they grade out as a situational pick — a 46.9% win rate, 0.1% pick rate, 1,605 ranked games sampled. On the power curve, Vayne is a scaling champion: comparatively weak early, but one of the strongest picks on the map once core items come online — so the plan is to survive the laning phase and take the game over late.
How Vayne wins: splitpushing a side lane and forcing the enemy to answer it, and using Vayne's mobility to catch isolated targets. The kit grades 8/10 split-push, 7/10 mobility. Play around where Vayne is thin, engage and siege (3/10, 3/10), and the enemy loses their angle.
The most-played core build is Experimental Hexplate, Essence Reaver, which holds a 36.1% win rate across 36 games this patch. The build above re-optimizes once you lock in the enemy composition.
And on the team side, Vayne gains the most from a Jinx (+9.5% pair win rate).
Most-played core build and runes for Vayne Mid this patch, from Emerald+ ranked games. Pick the enemy team at the top of the page for a comp-specific build.
Champions whose presence raises Vayne's win rate most as Mid, by pair WR delta over Vayne's solo performance.
Best Jungle partners for Vayne
Best ADC partners for VayneVayne is also played in these other roles this patch.
For full draft-time coaching with all 10 picks, use the Team Builder. To see Vayne's tier on this patch, see the Tier List.
