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A data-driven breakdown of Lissandra Mid for patch 16.17: the most-played and highest-win-rate builds and runes, the matchups that beat Lissandra, synergy partners, and how Lissandra closes games — all from ranked Emerald+ data.
Lissandra is an AP mage in the mid, and on patch 16.17 they grade out as a strong pick — a 53.1% win rate, 5.7% pick rate, 66,383 ranked games sampled. On the power curve, Lissandra spikes hardest in the mid game around the two-to-three-item mark — that is the window to force fights and objectives.
How Lissandra wins: grouped 5-v-5 teamfights, where Lissandra tips the fight, and landing engage and starting fights on Lissandra's terms. The kit grades 9/10 teamfighting, 8/10 engage, 7/10 waveclear. Lissandra grades low on split-push (2/10), so don't take fights that turn on those dimensions.
The most-played core build is Malignance, Shadowflame, Zhonya's Hourglass, which holds a 57.2% win rate across 6,341 games this patch. The build above re-optimizes once you lock in the enemy composition.
The matchup to respect is Swain, where Lissandra sits at just 42.6%, the lane swings the other way into Mel (63.3%), and on the team side, Lissandra gains the most from a Ambessa (+6.6% pair win rate).
The build Lissandra Mid players run most on patch 16.17, shown with its live win rate. Choose the enemy team up top to tailor it to the comp you are facing.
Champions that beat Lissandra Mid the most this patch, anywhere on the enemy team. Top ban targets.
The teammates that make Lissandra Mid stronger this patch, measured by how much the pair's win rate beats Lissandra going solo.
Best Top partners for Lissandra
Best Jungle partners for Lissandra
Best ADC partners for LissandraLissandra is also played in these other roles this patch.
Take Lissandra into the Team Builder to plan around every pick, or check the Tier List to see exactly where Lissandra ranks this patch.
